The rare and inexplicable Puberty Syndrome is thought of as a myth. It is a rare disease which only affects teenagers, and its symptoms are so supernatural that hardly anyone recognizes it as a legitimate occurrence. However, high school student Sakuta Azusagawa knows from personal experience that it is very much real, and happens to be quite prevalent in his school.
Mai Sakurajima is a third-year high school student who gained fame in her youth as a child actress, but recently halted her promising career for reasons unknown to the public. With an air of unapproachability, she is well known throughout the school, but none dare interact with her—that is until Sakuta sees her wandering the library in a bunny girl costume. Despite the getup, no one seems to notice her, and after confronting her, he realizes that she is another victim of Puberty Syndrome. As Sakuta tries to help Mai through her predicament, his actions bring him into contact with more girls afflicted with the elusive disease.
[Written by MAL Rewrite]+ More
More Seasons
Characters & Voice Actors

Azusagawa, Kaede
Supporting
Futaba, Rio
Supporting
Hanawa, Ryouko
Supporting
Hirokawa, Uzuki
Supporting
Kamisato, Saki
Supporting
Kano, Kotomi
Supporting
Kashiba, Rena
Supporting
Koga, Tomoe
SupportingRecommended for you
Tonikawa: Over the Moon for You - Uniform
Special
22m
The Infinitors
ONA
20m
Hanako
Movie
4m
Lookism
ONA
22m
Me & Roboco
TV
5m
Lupin Zero
ONA
30m
One Piece Film: Red
Movie
115m
Vinland Saga: 2nd Season
TV
25m
Bungo Stray Dogs 4
TV
23m
Onimai: I'm Now Your Sister!
TV
23m
Tomo-chan Is a Girl!
TV
23m
Spy Classroom
TV
23m